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1932

Q&A

She saw the obesity epidemic coming. Then an unexpected finding mired her in controversy.

Katherine Flegal was a scientist who found herself crunching numbers for the government, until one day her analyses set off a firestorm. What does she make of her decades as a woman in public health research?

Making microbots smart

What would it take to create a truly intelligent microbot, one that can operate independently? A roboticist describes the fascinating minutiae and the medical jobs these tiny machines could do for us.

Vaccinating the world against Covid-19

Lower-income countries haven’t gotten an equal share of lifesaving coronavirus vaccines. Older, more familiar vaccine technologies may hold the key to more equitable use, says Maria Elena Bottazzi.

To understand airborne transmission of disease, follow the flow

Viruses and bacteria travel in fluids, such as the air we breathe. Studying exhalations, toilet flushes and rain drops, with math and modeling, can sharpen the big-picture view of how to prevent infections.

Studying poverty through a child’s eyes

Research on early-life adversity should pay more attention to the perspective of children themselves

How health insurance is faring under Covid

Millions of Americans lost employer-sponsored coverage when Covid-19 disrupted their jobs. Can America come up with a better system?

Pandemic puts all eyes on public health

Covid-19 has exposed the weak spots of the US public health system — and that presents an opportunity, says an epidemiologist, for the nation to recognize the problems and act to fix them

Making and breaking connections in the brain

The links between nerve cells, called synapses, allow us to learn and adapt, and hold clues to conditions such as autism, schizophrenia and more

The trouble with medicating mental illness

Psychotropic drugs have severely narrowed how we treat psychiatric disorders — to the detriment of patients and society as a whole. A look at the past suggests a better way forward.

Speaking of pandemics: The art and science of risk communication

Public health messages should be loud and clear, so that everyone listens and stays safe. But that’s easier said than done — especially with a case as complex as Covid-19.

Building a mouse squad against Covid-19

It began with an email from Wuhan, a Maine laboratory and mouse sperm from Iowa. Now that lab is on the verge of supplying a much-needed animal for SARS-CoV-2 research.

Infectious disease: Making — and breaking — the animal connection

We know pathogens from other species can endanger us. Scientists are better equipped than ever to do something about it, but political buy-in is crucial.

Chasing the genes behind pain

New treatments for chronic pain face a long road despite promising developments. Research in people with rare diseases is pointing the way to genes that influence how we experience pain — and might lead to new medications.

Living with chronic illness: Why some cope and others don’t

What helps some people diagnosed with cancer, heart disease or diabetes stay relatively happy and healthy, while others are devastated? Psychologist Vicki Helgeson explains the traits and mindsets that can make the difference.

Profiling the perpetrators of past plagues

The ancient pathogens in old graves are as dead as the people they once infected. Still, they tell a vivid tale.

Measuring surgical quality

Not all surgeons are equally skilled with a scalpel. Doctors are developing new ways to test — and improve — operating room performance.

How maternal mood shapes the developing brain

Stress and anxiety during pregnancy can mean a higher risk of offspring developing ADHD, depression or other conditions. Medical psychologist Catherine Monk explains how prenatal mental care benefits mothers and babies.

Going gentle

A sociologist explains how to get the most out of the final months of life

Getting “exhausted” T cells back into action against cancer

When a malignancy or chronic infection sets in, a kind of immune combat fatigue can follow. Finding ways to recharge immune cells can restore their ability to fight deadly diseases, says immunologist John Wherry.

Always look on the bright side of life

How a positive outlook may buffer us from stress and ward off health problems 

Watching Alzheimer’s in action

A look inside the brains of engineered mice suggests therapies might need to target two key proteins — tau and amyloid-beta — at the same time

Bypassing paralysis

By decoding brain activity with electrical implants, computers can help disabled people move a robotic arm — or their own

Break on through: How some viruses infect the placenta

A few rare viruses can reach the fetus when pregnant women are infected, with tragic result. As explored in this Q&A, researchers are figuring out how the placenta acts as protector and how some pathogens slip through.

Humanizing immunology

The field has long been more mice than men. New technologies and systems-based approaches with human cells may soon fill gaps in our understanding of autoimmune disease and health, Mark Davis says in a Q&A.

Unhealthy work: Why migrants are especially vulnerable to injury and death on the job

A mysterious kidney disease is just one of the many health risks faced by immigrant laborers. In a Q&A, occupational health expert Marc Schenker discusses the hazards and a few potential solutions.

Managing pain in a time of opioid abuse

Other therapies, more training, a new mindset: Can doctors bring relief to patients without putting them at risk for addiction?

Why viruses deserve a better reputation

Sure they cause disease, but the microbes can be a help as well. Witness long-lasting pepper seeds, drought-resistant crop plants and even our own placentas.

Labor of love

Flipping the scientific thinking on our species’ “difficult childbirth”

Organs grown to order

Genetic advances may make it possible to grow transplantable tissues in other species. That could solve immunity and availability issues, but raises ethical concerns.

How to detect clandestine nuclear weapons programs

A “policy physicist” explores practical ways to sniff out uranium processing from afar

In promoting health, when to tiptoe — and when to stomp?

Inform, incentivize, legislate: There’s a ladder of escalating approaches for changing citizens’ behavior — and nudges for every rung

From academics to access, Harold Varmus reflects on the achievements and challenges in cancer research

The Nobel laureate and former NIH director talks about how far the field has come, where it should go and why some of the best discoveries in oncology still aren’t reaching patients who need them

Can marriage make you sick?

In general, it promotes health. But it might not if your relationship is troubled or your partner is ill. Here's why, and what can be done.

Balance, not carbs or fat, is the key to healthy eating

An expert’s view on a common-sense diet: Don’t fuss over details, and put more plants on the plate

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